ventromedial hypothalamic nuclei and feeding behavior
نویسندگان
چکیده
the role of the ventromedial nuclei of the hypothalamus (vmn) in food behavior was studied in adult male rats, allocated in 3 groups: control, sham and lesioned. electrolytic lesions were induced stereotaxically (1.2 ma, 15 sec). results revealed a significant decrease (p
منابع مشابه
VENTROMEDIAL HYPOTHALAMIC NUCLEI AND FEEDING BEHAVIOR
The role of the ventromedial nuclei of the hypothalamus (VMN) in food behavior was studied in adult male rats, allocated in 3 groups: control, sham and lesioned. Electrolytic lesions were induced stereotaxically (1.2 mA, 15 sec). Results revealed a significant decrease (p<O.05) in body weight (BW) and food intake (FI) in the order of lesioned <sham <control during the fIrst week. However, ...
متن کاملUrocortin in the ventromedial hypothalamic nucleus acts as an inhibitor of feeding behavior in rats.
Urocortin (UCN), a member of the corticotropin-releasing factor (CRF) family, inhibits food intake when it is injected intracerebroventricularly in rats. To explore the site of action of UCN in feeding behavior, we examined the effects of injection of UCN into various hypothalamic nuclei on food and water intake in 24-h fasted rats. Injection of UCN into the ventromedial hypothalamic nucleus (V...
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Leptin has profound effects on feeding, metabolism, and neuroendocrine status. Evidence indicates that the hypothalamus coordinates these responses, though the specific brain pathways engaged by leptin remain obscure. The paraventricular nucleus of the hypothalamus (PVH) regulates pituitary gland function and feeding, and innervates autonomic preganglionic neurons, making it a candidate to regu...
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Numerous studies have demonstrated that the hypothalamic ventromedial nuclei (VMN) regulate energy homeostasis by integrating and utilizing behavioral and metabolic mechanisms. The VMN heavily express pituitary adenylate cyclase-activating polypeptide (PACAP) type I receptors (PAC1R). Despite the receptor distribution, most PACAP experiments investigating affects on feeding have focused on intr...
متن کاملCombination unilateral amygdaloid and ventromedial hypothalamic lesions: evidence for a feeding pathway.
Previous studies have reported hyperphagia and obesity in female rats with bilateral lesions of the most posterodorsal part of the amygdala. In rats with unilateral posterodorsal amygdaloid lesions, a dense pattern of anterograde degeneration appears in the ipsilateral ventromedial hypothalamus, but not the contralateral nucleus. In the present study, female rats with unilateral ventromedial hy...
متن کاملOxytocin in the ventromedial hypothalamic nucleus reduces feeding and acutely increases energy expenditure.
Central oxytocin reduces food intake and increases energy expenditure. The ventromedial hypothalamic nucleus (VMN) is associated with energy balance and contains a high density of oxytocin receptors. We hypothesized that oxytocin in the VMN is a negative regulator of energy balance acting to reduce feeding and increase energy expenditure. To test this idea, oxytocin or vehicle was injected dire...
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عنوان ژورنال:
medical journal of islamic republic of iranجلد ۱۱، شماره ۲، صفحات ۱۲۷-۱۳۱
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